My goal is to develop close collaborations with strong experimental and theoretical components. By blending cross and inter-disciplinary expertise we hope to expand scientific inquiry in new and exciting directions.

General reports on our research:

Current Research Support

  • NSF MCB 1715826, Systems Biology of Heterotrimeric G-protein Signaling in Overlapping Stomatal Closure Pathways (co-PI)
  • NSF IIS 1814405, Collaborative Research: Network Analysis and Anomaly Detection via Global Curvatures (PI)
  • ARO MURI, Transport in Disordered Hyperuniform Systems and Networks (co-PI)

Current Research Group

Ph.D Candidates

Eli Newby
Fatemeh Nasrollahi
Kyu Hyong Park

Research Group Alumni

Ph.D. Alumni

Assieh Saadatpour
Claire Christensen
Colin Campbell
Gang Yang
Hari Thadakamalla
Jordan Rozum
Nandini Raghavan
Parul Maheshwari
Ranran Zhang
Song Li
Steven Steinway
Zhongyao Sun

Postdoctoral Alumni

David Wooten
Jaewook Joo
Jorge G. T. Zanudo
Juilee Thakar
Rui-Sheng Wang
Suann Yang
Xiao Gan

Research Areas

Signal transduction in plant guard cells


Plants have developed sophisticated signal transduction mechanisms to be able to respond to changing environmental conditions. One such mechanism is the opening of stomata (pores) to light and closing them in response to drought conditions. We have synthesized experimental information on light and drought signaling to reconstruct and model the signal transduction network of guard cells. Our work has identified knowledge gaps and has generated new predictions and hypotheses.


  • Prof. Sarah Assmann, Waller Professor of Biology, Department of Biology, Penn State

Modeling ecological communities


Relationships such as those between predators and prey, or symbiotic interactions like those of plants and insect pollinators, link the species of an ecological community into a complex network of interdependence. This means that the demise of one species can have knock-on effects that are hard to predict and may occasionally be catastrophic. We analyzed the effects of perturbations, interventions and restoration strategies in prototypical plant-pollinator networks


  • Prof. Katriona Shea, Professor of Biology, Penn State
  • Prof. Colin Campbell, Associate Professor of Physics, University of Mount Union

Elucidating the attractor repertoire of biological systems


We are developing methods to identify and understand system-level decision-making, i.e., robust commitment toward one of the dynamical attractors in a multistable system. We implemented these methods for Boolean systems and have generalized them to multi-level discrete dynamical systems and continuous (ODE) systems.